Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5001999..5002420 Replicon chromosome
Accession NZ_CP110309
Organism Xanthomonas phaseoli pv. phaseoli strain CFBP 7423

Toxin (Protein)


Gene name higB Uniprot ID A0A3Q9Q4S9
Locus tag OM947_RS21695 Protein ID WP_017156024.1
Coordinates 5002307..5002420 (-) Length 38 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OM947_RS21690 Protein ID WP_017156025.1
Coordinates 5001999..5002289 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM947_RS21665 (OM947_21665) 4997334..4997666 + 333 WP_003482333.1 hypothetical protein -
OM947_RS21675 (OM947_21675) 4997981..4999906 + 1926 WP_039574551.1 M61 family metallopeptidase -
OM947_RS21680 (OM947_21680) 4999974..5000153 + 180 WP_039574549.1 hypothetical protein -
OM947_RS21685 (OM947_21685) 5000256..5001644 - 1389 WP_039574546.1 type III secretion system effector XopQ -
OM947_RS21690 (OM947_21690) 5001999..5002289 - 291 WP_017156025.1 HigA family addiction module antitoxin Antitoxin
OM947_RS21695 (OM947_21695) 5002307..5002420 - 114 WP_017156024.1 hypothetical protein Toxin
OM947_RS21700 (OM947_21700) 5002685..5005192 - 2508 WP_046834789.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4957173..5026328 69155


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4677.41 Da        Isoelectric Point: 9.1273

>T263605 WP_017156024.1 NZ_CP110309:c5002420-5002307 [Xanthomonas phaseoli pv. phaseoli]
MKGERRGQYRIRINDRWRICVRWMEGDVVQVEIIDYH

Download         Length: 114 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10387.09 Da        Isoelectric Point: 9.0188

>AT263605 WP_017156025.1 NZ_CP110309:c5002289-5001999 [Xanthomonas phaseoli pv. phaseoli]
MTVLPNIHPGAILLEEFLQPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTFERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q9Q4S9

Antitoxin

Source ID Structure

References