Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4981674..4982095 Replicon chromosome
Accession NZ_CP110306
Organism Xanthomonas phaseoli pv. phaseoli strain BB075a

Toxin (Protein)


Gene name higB Uniprot ID A0A3Q9Q4S9
Locus tag OM949_RS21590 Protein ID WP_017156024.1
Coordinates 4981982..4982095 (-) Length 38 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OM949_RS21585 Protein ID WP_017156025.1
Coordinates 4981674..4981964 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM949_RS21560 (OM949_21560) 4977009..4977341 + 333 WP_003482333.1 hypothetical protein -
OM949_RS21570 (OM949_21570) 4977656..4979581 + 1926 WP_039574551.1 M61 family metallopeptidase -
OM949_RS21575 (OM949_21575) 4979649..4979828 + 180 WP_039574549.1 hypothetical protein -
OM949_RS21580 (OM949_21580) 4979931..4981319 - 1389 WP_039574546.1 type III secretion system effector XopQ -
OM949_RS21585 (OM949_21585) 4981674..4981964 - 291 WP_017156025.1 HigA family addiction module antitoxin Antitoxin
OM949_RS21590 (OM949_21590) 4981982..4982095 - 114 WP_017156024.1 hypothetical protein Toxin
OM949_RS21595 (OM949_21595) 4982360..4984867 - 2508 WP_046834789.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4935649..5006003 70354


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4677.41 Da        Isoelectric Point: 9.1273

>T263602 WP_017156024.1 NZ_CP110306:c4982095-4981982 [Xanthomonas phaseoli pv. phaseoli]
MKGERRGQYRIRINDRWRICVRWMEGDVVQVEIIDYH

Download         Length: 114 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10387.09 Da        Isoelectric Point: 9.0188

>AT263602 WP_017156025.1 NZ_CP110306:c4981964-4981674 [Xanthomonas phaseoli pv. phaseoli]
MTVLPNIHPGAILLEEFLQPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTFERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q9Q4S9

Antitoxin

Source ID Structure

References