Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5035657..5036078 Replicon chromosome
Accession NZ_CP110303
Organism Xanthomonas phaseoli pv. phaseoli strain BB013a

Toxin (Protein)


Gene name higB Uniprot ID A0A3Q9Q4S9
Locus tag OM952_RS21935 Protein ID WP_017156024.1
Coordinates 5035965..5036078 (-) Length 38 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag OM952_RS21930 Protein ID WP_264685101.1
Coordinates 5035657..5035947 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM952_RS21905 (OM952_21905) 5030992..5031324 + 333 WP_003482333.1 hypothetical protein -
OM952_RS21915 (OM952_21915) 5031639..5033564 + 1926 WP_039574551.1 M61 family metallopeptidase -
OM952_RS21920 (OM952_21920) 5033632..5033811 + 180 WP_039574549.1 hypothetical protein -
OM952_RS21925 (OM952_21925) 5033914..5035302 - 1389 WP_039574546.1 type III secretion system effector XopQ -
OM952_RS21930 (OM952_21930) 5035657..5035947 - 291 WP_264685101.1 HigA family addiction module antitoxin Antitoxin
OM952_RS21935 (OM952_21935) 5035965..5036078 - 114 WP_017156024.1 hypothetical protein Toxin
OM952_RS21940 (OM952_21940) 5036075..5036248 - 174 WP_201443182.1 hypothetical protein -
OM952_RS21945 (OM952_21945) 5036343..5038850 - 2508 WP_046834789.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4985620..5059986 74366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(14-63)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4677.41 Da        Isoelectric Point: 9.1273

>T263598 WP_017156024.1 NZ_CP110303:c5036078-5035965 [Xanthomonas phaseoli pv. phaseoli]
MKGERRGQYRIRINDRWRICVRWMEGDVVQVEIIDYH

Download         Length: 114 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10374.14 Da        Isoelectric Point: 11.0968

>AT263598 WP_264685101.1 NZ_CP110303:c5035947-5035657 [Xanthomonas phaseoli pv. phaseoli]
MTVLPNIHPGAILLEEFLQPLGISQNALARATGVPPRRIKKSVLGKRGITADTAVRLAAALGTFERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q9Q4S9

Antitoxin

Source ID Structure

References