Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrG-as-bsrG/-
Location 2273615..2273865 Replicon chromosome
Accession NC_017190
Organism Bacillus amyloliquefaciens LL3

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag LL3_RS21095 Protein ID WP_009967548.1
Coordinates 2273615..2273731 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 2273726..2273865 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL3_RS11380 2268659..2270470 - 1812 WP_014472054.1 reverse transcriptase/maturase family protein -
LL3_RS11385 2271022..2271732 - 711 WP_014472055.1 lesion bypass phage DNA polymerase -
LL3_RS11390 2271725..2272057 - 333 WP_014472056.1 YolD-like family protein -
LL3_RS11395 2272275..2273033 - 759 WP_080558536.1 sporulation protein YunB -
LL3_RS11400 2273162..2273365 - 204 WP_041915578.1 hypothetical protein -
LL3_RS21095 2273615..2273731 + 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
- 2273726..2273865 - 140 NuclAT_0 - Antitoxin
- 2273726..2273865 - 140 NuclAT_0 - Antitoxin
- 2273726..2273865 - 140 NuclAT_0 - Antitoxin
- 2273726..2273865 - 140 NuclAT_0 - Antitoxin
LL3_RS11405 2274039..2274599 - 561 WP_014472060.1 SMI1/KNR4 family protein -
LL3_RS11410 2274599..2276353 - 1755 WP_014472061.1 hypothetical protein -
LL3_RS11415 2276525..2277508 + 984 WP_014472062.1 thermonuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2126041..2279300 153259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-38)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T26358 WP_009967548.1 NC_017190:2273615-2273731 [Bacillus amyloliquefaciens LL3]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp

>T26358 NC_017190:2273615-2273731 [Bacillus amyloliquefaciens LL3]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 140 bp

>AT26358 NC_017190:c2273865-2273726 [Bacillus amyloliquefaciens LL3]
AAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCACCCCGGCTCTGTACGAAAAGCTGCCCATCAAAGGGCTTGCTCG
ATGTTGAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9

Antitoxin

Download structure file

References