Detailed information of TA system TA263579

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 2730375..2730712
• Replicon: chromosome
• Accession: NZ_CP110289
• Organism: Enterococcus faecalis strain AKSZ-208

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: MZO28_RS13545
• Protein ID: WP_073437820.1
• Coordinates: 2730375..2730518 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2730450..2730712 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZO28_RS13525	2726467..2727105	-	639	WP_073438309.1	lytic polysaccharide monooxygenase	-
MZO28_RS13530	2727791..2729407	+	1617	WP_002406969.1	phosphatase PAP2/LCP family protein	-
MZO28_RS13535	2729736..2729885	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	-
MZO28_RS13540	2730004..2730144	+	141	WP_073340360.1	putative holin-like toxin	-
MZO28_RS13545	2730375..2730518	+	144	WP_073437820.1	putative holin-like toxin	Toxin
-	2730450..2730712	-	263	-	-	Antitoxin
MZO28_RS13550	2730713..2735404	-	4692	WP_085345106.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5274.27 Da
• Isoelectric Point: 8.6626

>T263579 WP_073437820.1 NZ_CP110289:2730375-2730518 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFEILEAVKENNKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 263 bp

>AT263579 NZ_CP110289:c2730712-2730450 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGGCGTTGTGCTACA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATATCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTTTTCTTTTACAGCCTCTAGGATTTCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Structures

Antitoxin