Detailed information of TA system TA263568

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2651111..2651373
• Replicon: chromosome
• Accession: NZ_CP110289
• Organism: Enterococcus faecalis strain AKSZ-208

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: MZO28_RS13190
• Protein ID: WP_002367458.1
• Coordinates: 2651230..2651373 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2651111..2651297 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZO28_RS13175	2646568..2649312	+	2745	WP_002411259.1	glycosyl hydrolase family 65 protein	-
MZO28_RS13180	2649327..2649977	+	651	WP_002389419.1	beta-phosphoglucomutase	-
MZO28_RS13185	2650397..2650990	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	2651111..2651297	+	187	-	-	Antitoxin
MZO28_RS13190	2651230..2651373	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
MZO28_RS13195	2651605..2652576	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
MZO28_RS13200	2652751..2653188	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
MZO28_RS13205	2653321..2653875	-	555	WP_002389433.1	nucleoside triphosphate pyrophosphatase	-
MZO28_RS13210	2653900..2656032	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T263568 WP_002367458.1 NZ_CP110289:c2651373-2651230 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT263568 NZ_CP110289:2651111-2651297 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin