Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4041903..4042149 Replicon chromosome
Accession NZ_CP110260
Organism Escherichia albertii strain KBSW16i

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag N6N74_RS19810 Protein ID WP_000956458.1
Coordinates 4041997..4042149 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 4041903..4041955 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N74_RS19795 4037307..4039106 + 1800 WP_113623171.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
N6N74_RS19800 4039106..4040818 + 1713 WP_044708375.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
N6N74_RS19805 4040998..4041732 + 735 WP_059214466.1 phosphoadenosine phosphosulfate reductase -
- 4041903..4041955 - 53 - - Antitoxin
N6N74_RS19810 4041997..4042149 + 153 WP_000956458.1 Hok/Gef family protein Toxin
N6N74_RS19815 4042275..4043312 - 1038 WP_059253936.1 aminopeptidase -
N6N74_RS19820 4043565..4044473 + 909 WP_000372392.1 sulfate adenylyltransferase subunit CysD -
N6N74_RS19825 4044475..4045902 + 1428 WP_054412002.1 sulfate adenylyltransferase subunit CysN -
N6N74_RS19830 4045902..4046507 + 606 WP_024164730.1 adenylyl-sulfate kinase -
N6N74_RS19835 4046557..4046880 + 324 WP_044711292.1 DUF3561 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T263513 WP_000956458.1 NZ_CP110260:4041997-4042149 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 53 bp

>AT263513 NZ_CP110260:c4041955-4041903 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References