Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-agrB/SymE(toxin)
Location 3914916..3915328 Replicon chromosome
Accession NZ_CP110258
Organism Escherichia albertii strain KBSW50i

Toxin (Protein)


Gene name symE Uniprot ID A0A8D9PK47
Locus tag N6N69_RS19015 Protein ID WP_000132619.1
Coordinates 3914987..3915328 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name agrB
Locus tag -
Coordinates 3914916..3914992 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N69_RS19005 (3911555) 3911555..3913024 + 1470 WP_016159453.1 type I restriction-modification system subunit M -
N6N69_RS19010 (3913024) 3913024..3914766 + 1743 WP_103054261.1 restriction endonuclease subunit S -
- (3914916) 3914916..3914992 - 77 NuclAT_6 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_6 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_6 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_6 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_7 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_7 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_7 - Antitoxin
- (3914916) 3914916..3914992 - 77 NuclAT_7 - Antitoxin
N6N69_RS19015 (3914987) 3914987..3915328 + 342 WP_000132619.1 endoribonuclease SymE Toxin
N6N69_RS19020 (3915490) 3915490..3916869 + 1380 WP_059217670.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
N6N69_RS19025 (3916869) 3916869..3917915 + 1047 WP_072252312.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
N6N69_RS19030 (3917971) 3917971..3919049 - 1079 Protein_3718 DUF1998 domain-containing protein -
N6N69_RS19035 (3919364) 3919364..3920295 - 932 Protein_3719 Rpn family recombination-promoting nuclease/putative transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3907947..3926600 18653


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12322.13 Da        Isoelectric Point: 7.8219

>T263491 WP_000132619.1 NZ_CP110258:3914987-3915328 [Escherichia albertii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAPEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT263491 NZ_CP110258:c3914992-3914916 [Escherichia albertii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References