Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3838121..3838379 Replicon chromosome
Accession NZ_CP110258
Organism Escherichia albertii strain KBSW50i

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag N6N69_RS18630 Protein ID WP_000809168.1
Coordinates 3838227..3838379 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3838121..3838178 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N69_RS18610 3834077..3834313 - 237 Protein_3637 arylsulfatase -
N6N69_RS18620 3835560..3836822 - 1263 Protein_3639 sulfatase-like hydrolase/transferase -
N6N69_RS18625 3836843..3837604 - 762 WP_001276206.1 outer membrane protein OmpK -
- 3838121..3838178 - 58 - - Antitoxin
N6N69_RS18630 3838227..3838379 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
N6N69_RS18635 3838487..3839617 - 1131 WP_001118445.1 molecular chaperone DnaJ -
N6N69_RS18640 3839706..3841622 - 1917 WP_000516135.1 molecular chaperone DnaK -
N6N69_RS18645 3841997..3842401 + 405 WP_000833521.1 DUF2541 family protein -
N6N69_RS18650 3842428..3843141 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T263490 WP_000809168.1 NZ_CP110258:3838227-3838379 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT263490 NZ_CP110258:c3838178-3838121 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References