Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 1054297..1054542 Replicon chromosome
Accession NZ_CP110258
Organism Escherichia albertii strain KBSW50i

Toxin (Protein)


Gene name hokX Uniprot ID L4J2K8
Locus tag N6N69_RS05060 Protein ID WP_000956460.1
Coordinates 1054390..1054542 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 1054297..1054345 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N69_RS05045 1049796..1051595 + 1800 WP_103053841.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -
N6N69_RS05050 1051595..1053307 + 1713 WP_103053840.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
N6N69_RS05055 1053392..1054126 + 735 WP_059228192.1 phosphoadenosine phosphosulfate reductase -
- 1054297..1054345 - 49 - - Antitoxin
N6N69_RS05060 1054390..1054542 + 153 WP_000956460.1 Hok/Gef family protein Toxin
N6N69_RS05065 1054706..1055818 - 1113 WP_059228194.1 IS4-like element IS421 family transposase -
N6N69_RS05070 1056071..1058728 + 2658 WP_123057910.1 CRISPR-associated helicase Cas3' -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1054706..1055818 1112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5602.81 Da        Isoelectric Point: 7.7899

>T263482 WP_000956460.1 NZ_CP110258:1054390-1054542 [Escherichia albertii]
MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

Antitoxin


Download         Length: 49 bp

>AT263482 NZ_CP110258:c1054345-1054297 [Escherichia albertii]
GTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829G7J5

Antitoxin

Download structure file

References