Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 597710..598509 Replicon chromosome
Accession NZ_CP110258
Organism Escherichia albertii strain KBSW50i

Toxin (Protein)


Gene name yhaV Uniprot ID A0A8H9C2I0
Locus tag N6N69_RS03005 Protein ID WP_059227548.1
Coordinates 597710..598174 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag N6N69_RS03010 Protein ID WP_103053959.1
Coordinates 598174..598509 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N69_RS02975 (592711) 592711..593145 - 435 WP_000948824.1 PTS galactosamine/N-acetylgalactosamine transporter subunit IIA -
N6N69_RS02980 (593163) 593163..594041 - 879 WP_001295548.1 PTS N-acetylgalactosamine transporter subunit IID -
N6N69_RS02985 (594031) 594031..594810 - 780 WP_000406226.1 PTS N-acetylgalactosamine transporter subunit IIC -
N6N69_RS02990 (594821) 594821..595294 - 474 WP_002461030.1 PTS N-acetylgalactosamine transporter subunit IIB -
N6N69_RS02995 (595317) 595317..596597 - 1281 WP_262930512.1 tagatose-bisphosphate aldolase subunit KbaZ -
N6N69_RS03000 (596846) 596846..597655 + 810 WP_103053960.1 aga operon transcriptional regulator AgaR -
N6N69_RS03005 (597710) 597710..598174 - 465 WP_059227548.1 type II toxin-antitoxin system ribonuclease toxin YhaV Toxin
N6N69_RS03010 (598174) 598174..598509 - 336 WP_103053959.1 type II toxin-antitoxin system antitoxin PrlF Antitoxin
N6N69_RS03015 (598658) 598658..600229 - 1572 WP_103053958.1 galactarate dehydratase -
N6N69_RS03020 (600600) 600600..601934 + 1335 WP_262930511.1 galactarate/glucarate/glycerate transporter GarP -
N6N69_RS03025 (601950) 601950..602720 + 771 WP_059235438.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17819.26 Da        Isoelectric Point: 9.7301

>T263479 WP_059227548.1 NZ_CP110258:c598174-597710 [Escherichia albertii]
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRFRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTQETEEKH

Download         Length: 465 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12336.89 Da        Isoelectric Point: 4.5392

>AT263479 WP_103053959.1 NZ_CP110258:c598509-598174 [Escherichia albertii]
MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHYEILPGGQVFMCRQGDEQEDHTMNAFLRFLDADIQNN
PQKTRPFDIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References