Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6177208..6177787 Replicon chromosome
Accession NZ_CP110128
Organism Pseudomonas sp. WJP1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OH720_RS27780 Protein ID WP_272603630.1
Coordinates 6177208..6177486 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OH720_RS27785 Protein ID WP_180204523.1
Coordinates 6177500..6177787 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH720_RS27760 (OH720_27770) 6172787..6172954 - 168 WP_272603627.1 DUF2474 domain-containing protein -
OH720_RS27765 (OH720_27775) 6173036..6174043 - 1008 WP_272603628.1 cytochrome d ubiquinol oxidase subunit II -
OH720_RS27770 (OH720_27780) 6174047..6175483 - 1437 WP_272603629.1 cytochrome ubiquinol oxidase subunit I -
OH720_RS27775 (OH720_27785) 6175885..6177123 + 1239 WP_008066098.1 MFS transporter -
OH720_RS27780 (OH720_27790) 6177208..6177486 + 279 WP_272603630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH720_RS27785 (OH720_27795) 6177500..6177787 + 288 WP_180204523.1 HigA family addiction module antitoxin Antitoxin
OH720_RS27790 (OH720_27800) 6177794..6178345 - 552 WP_008066096.1 DJ-1/PfpI family protein -
OH720_RS27795 (OH720_27805) 6178414..6178863 - 450 WP_272603631.1 DUF4879 domain-containing protein -
OH720_RS27800 (OH720_27810) 6179084..6180379 + 1296 WP_008066092.1 NCS2 family permease -
OH720_RS27805 (OH720_27815) 6180376..6181455 + 1080 WP_272603632.1 tRNA (uridine(54)-C5)-methyltransferase TrmA -
OH720_RS27810 (OH720_27820) 6181510..6181956 - 447 WP_272603633.1 hypothetical protein -
OH720_RS27815 (OH720_27825) 6181953..6182381 - 429 WP_272603634.1 DUF4160 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(3-91)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10697.22 Da        Isoelectric Point: 9.5306

>T263178 WP_272603630.1 NZ_CP110128:6177208-6177486 [Pseudomonas sp. WJP1]
MIRSFQHKGLRGFYETGSTRGIRADHAKRLGRMLQFMDRAAVPGDLDLPGWRLHPLKGELAEYWSLTVSGNWRVIFRFTG
SDIELVDYLDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10515.19 Da        Isoelectric Point: 7.1424

>AT263178 WP_180204523.1 NZ_CP110128:6177500-6177787 [Pseudomonas sp. WJP1]
MPMHNPPHPGETLLMDVLPELGISVAELARHLGFARPHLSRVLHGHAPVSPDLAVRLERAGIGKARMWLGVQTDYDLWQA
EQREQPPIKPIAAHA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References