Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1838413..1839071 Replicon chromosome
Accession NZ_CP110114
Organism Arthrobacter sp. YA7-1

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag OIT41_RS08570 Protein ID WP_264637783.1
Coordinates 1838413..1838766 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag OIT41_RS08575 Protein ID WP_264637784.1
Coordinates 1838766..1839071 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIT41_RS08555 (OIT41_08555) 1834679..1835767 + 1089 WP_241711099.1 IS630 family transposase -
OIT41_RS08560 (OIT41_08560) 1835754..1836746 - 993 WP_264637781.1 hypothetical protein -
OIT41_RS08565 (OIT41_08565) 1837217..1838113 - 897 WP_264637782.1 YaaC family protein -
OIT41_RS08570 (OIT41_08570) 1838413..1838766 + 354 WP_264637783.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OIT41_RS08575 (OIT41_08575) 1838766..1839071 + 306 WP_264637784.1 helix-turn-helix domain-containing protein Antitoxin
OIT41_RS08580 (OIT41_08580) 1839619..1840506 - 888 WP_264637785.1 PIN domain-containing protein -
OIT41_RS08585 (OIT41_08585) 1840583..1841302 + 720 WP_264637786.1 hypothetical protein -
OIT41_RS08590 (OIT41_08590) 1841590..1842234 - 645 WP_264637787.1 nuclease-related domain-containing protein -
OIT41_RS08595 (OIT41_08595) 1842710..1842847 + 138 WP_264637788.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1826010..1894877 68867


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-84)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13249.11 Da        Isoelectric Point: 5.6660

>T263124 WP_264637783.1 NZ_CP110114:1838413-1838766 [Arthrobacter sp. YA7-1]
VWNVDVELVESWLLGLDQDSYEQVIAALELLAERGPQLGRPLVDTVVRSRHKNMKELRPGSSGRSELRILFAFDPERHAI
LLVAGDKAGSWSKWYRTNIPIADELFDDHLRILKGGS

Download         Length: 354 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11589.31 Da        Isoelectric Point: 7.2066

>AT263124 WP_264637784.1 NZ_CP110114:1838766-1839071 [Arthrobacter sp. YA7-1]
MAKTIEEMLAKRPVDRVAVDALKKQLLDEVRAYRLRELREASDLTQVELAARLHVSQNRVSRIEHGDIDRAQVDTLRKYV
EAVGGRLRVEVELGDERIQIA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References