263091

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2249801..2251164 Replicon chromosome
Accession NZ_CP110080
Organism Buttiauxella sp. WJP83

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag OH773_RS10485 Protein ID WP_270145495.1
Coordinates 2249801..2250850 (-) Length 350 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag OH773_RS10490 Protein ID WP_270145496.1
Coordinates 2250850..2251164 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH773_RS10450 (OH773_10450) 2245226..2245414 - 189 WP_183270253.1 YegP family protein -
OH773_RS10455 (OH773_10455) 2245582..2245755 + 174 WP_270145487.1 GhoT/OrtT family toxin -
OH773_RS10460 (OH773_10460) 2245786..2246100 + 315 WP_270145489.1 N(4)-acetylcytidine aminohydrolase -
OH773_RS10465 (OH773_10465) 2246146..2246361 - 216 WP_183269289.1 YdcH family protein -
OH773_RS10470 (OH773_10470) 2246637..2247398 + 762 WP_270145492.1 siderophore-interacting protein -
OH773_RS10475 (OH773_10475) 2247409..2248005 + 597 WP_270145493.1 PadR family transcriptional regulator -
OH773_RS10480 (OH773_10480) 2248092..2249756 + 1665 WP_270145494.1 methyl-accepting chemotaxis protein -
OH773_RS10485 (OH773_10485) 2249801..2250850 - 1050 WP_270145495.1 HipA domain-containing protein Toxin
OH773_RS10490 (OH773_10490) 2250850..2251164 - 315 WP_270145496.1 HipA N-terminal domain-containing protein Antitoxin
OH773_RS10495 (OH773_10495) 2251149..2251472 - 324 WP_270145497.1 helix-turn-helix domain-containing protein -
OH773_RS10500 (OH773_10500) 2251786..2252808 + 1023 WP_270145498.1 MsnO8 family LLM class oxidoreductase -
OH773_RS10505 (OH773_10505) 2252819..2253955 + 1137 WP_270145499.1 amidohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(61-261)

Antitoxin

HipA, N-terminal subdomain 1

(5-99)


Sequences

Toxin        


Download         Length: 350 a.a.        Molecular weight: 39359.12 Da        Isoelectric Point: 6.6186

>T263091 WP_270145495.1 NZ_CP110080:c2250850-2249801 [Buttiauxella sp. WJP83]
MMGLPPRCHILLTPLVQAKEQESGYSTKGLRHLTGSGKVNPKLSFTRSEFIHELPKAQRGMSISGYQPKLQMVVQDGEFA
VVEHQGEYILKPSPAEFPHLAENEHATMTLMARLGFDVPPHGLVSFAPEQDEPRELAFVIRRFDRDRQTGAAIHQEQLDA
AMNVGEKYGKTGSDGKQYVSYQQLAEFLTQHVNSNIAFKVDLFRRIAYAYLLGNNDMHLRNFGLIHPRIGEPSLSPVYDF
VSVAPYPAIFSSGFMALPLLSCEEGDRELAPGFKTAYGEYLGMDFHALGLSMGMTDKLIVKLLHDLQKESRIVDAVYRES
FMPVKDVEATLRCYHQRLDRLMRLDEAQI

Download         Length: 1050 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12051.68 Da        Isoelectric Point: 5.8504

>AT263091 WP_270145496.1 NZ_CP110080:c2251164-2250850 [Buttiauxella sp. WJP83]
MRRRVEVWLYGEPVGELRQDNDGYEFSYRADYIGPPLSLSLPVRVGRFRSQTLPPFFSSLAPEGWLKKRYSQLQQRDEHD
LLGMLIDNGKNLIGAVQLVNIQED

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References