Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1583896..1584542 Replicon chromosome
Accession NZ_CP110080
Organism Buttiauxella sp. WJP83

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OH773_RS07335 Protein ID WP_270144388.1
Coordinates 1583896..1584249 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OH773_RS07340 Protein ID WP_270144389.1
Coordinates 1584246..1584542 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH773_RS07325 (OH773_07325) 1579168..1582302 - 3135 WP_270144385.1 MdtB/MuxB family multidrug efflux RND transporter permease subunit -
OH773_RS07330 (OH773_07330) 1582302..1583540 - 1239 WP_270144387.1 MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit -
OH773_RS07335 (OH773_07335) 1583896..1584249 + 354 WP_270144388.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH773_RS07340 (OH773_07340) 1584246..1584542 + 297 WP_270144389.1 XRE family transcriptional regulator Antitoxin
OH773_RS07345 (OH773_07345) 1584575..1585933 - 1359 WP_270144390.1 molecular chaperone -
OH773_RS07350 (OH773_07350) 1586055..1586945 + 891 WP_270144392.1 DNA-3-methyladenine glycosylase 2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(7-88)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13870.99 Da        Isoelectric Point: 8.6754

>T263086 WP_270144388.1 NZ_CP110080:1583896-1584249 [Buttiauxella sp. WJP83]
MAWTVIYTDDFYCWYNEQPLDLRKRIVAMTLNISVWGPQLGRPLADTVKGSRFTNMKELRVQWCGKPYRLFFAFDPLQRA
VVLCGGDKTGRKRFYGDLIRLADTQFSRYLDEMERDE

Download         Length: 354 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11175.07 Da        Isoelectric Point: 4.8409

>AT263086 WP_270144389.1 NZ_CP110080:1584246-1584542 [Buttiauxella sp. WJP83]
MKKLQDVMAEFSPEDQNDIWRMAQELVLETGLQLMREELQFSQKQVAEVMGVTQPAIAAIEQRGNDLKVLTLKRYIEAMG
GKLSLLVQLPEGNKVFRI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References