Detailed information of TA system TA263067

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2715984..2716246
• Replicon: chromosome
• Accession: NZ_CP110074
• Organism: Enterococcus faecalis strain BE5

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM06_RS13455
• Protein ID: WP_002367458.1
• Coordinates: 2716103..2716246 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2715984..2716170 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM06_RS13440	2711441..2714185	+	2745	WP_264563347.1	glycosyl hydrolase family 65 protein	-
OLM06_RS13445	2714200..2714850	+	651	WP_002389419.1	beta-phosphoglucomutase	-
OLM06_RS13450	2715270..2715863	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	2715984..2716170	+	187	-	-	Antitoxin
OLM06_RS13455	2716103..2716246	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
OLM06_RS13460	2716478..2717449	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
OLM06_RS13465	2717624..2718061	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
OLM06_RS13470	2718194..2718748	-	555	WP_002354869.1	Maf family protein	-
OLM06_RS13475	2718773..2720905	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T263067 WP_002367458.1 NZ_CP110074:c2716246-2716103 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT263067 NZ_CP110074:2715984-2716170 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin