Detailed information of TA system TA263059

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2644444..2644701
• Replicon: chromosome
• Accession: NZ_CP110074
• Organism: Enterococcus faecalis strain BE5

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM06_RS13120
• Protein ID: WP_021164441.1
• Coordinates: 2644600..2644701 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2644444..2644651 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM06_RS13095	2640128..2641081	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
OLM06_RS13100	2641120..2641875	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLM06_RS13105	2641872..2642837	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
OLM06_RS13110	2642834..2643781	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLM06_RS13115	2643966..2644418	+	453	WP_002389410.1	YueI family protein	-
-	2644444..2644651	+	208	-	-	Antitoxin
OLM06_RS13120	2644600..2644701	-	102	WP_021164441.1	putative holin-like toxin	Toxin
OLM06_RS13125	2645033..2645134	-	102	WP_075551663.1	putative holin-like toxin	-
OLM06_RS13130	2645324..2647594	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLM06_RS13135	2647765..2648265	+	501	WP_002372831.1	cysteine hydrolase family protein	-
OLM06_RS13140	2648664..2649560	+	897	WP_002389477.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T263059 WP_021164441.1 NZ_CP110074:c2644701-2644600 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 208 bp

>AT263059 NZ_CP110074:2644444-2644651 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATAAAGATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTAT
TTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin