Detailed information of TA system TA263057

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 571113..571345
• Replicon: chromosome
• Accession: NZ_CP110074
• Organism: Enterococcus faecalis strain BE5

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM06_RS02890
• Protein ID: WP_033606579.1
• Coordinates: 571113..571229 (+)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	571140..571345 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM06_RS02880	566551..568809	+	2259	WP_002363179.1	DNA helicase PcrA	-
OLM06_RS02885	568935..570965	+	2031	WP_002389576.1	NAD-dependent DNA ligase LigA	-
OLM06_RS02890	571113..571229	+	117	WP_033606579.1	putative holin-like toxin	Toxin
-	571140..571345	-	206	-	-	Antitoxin
OLM06_RS02895	571547..571852	+	306	WP_002355569.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
OLM06_RS02900	571852..573321	+	1470	WP_002368026.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	-
OLM06_RS02905	573321..574751	+	1431	WP_002358703.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	-
OLM06_RS02910	574770..575858	+	1089	WP_002355572.1	diacylglycerol kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4073.99 Da
• Isoelectric Point: 5.9482

>T263057 WP_033606579.1 NZ_CP110074:571113-571229 [Enterococcus faecalis]
MLLSVEAALGLMISFAILVVTIIFGILALVLDNKNNRS

Nucleotide

• Length: 117 bp

Antitoxin

Nucleotide

• Length: 206 bp

>AT263057 NZ_CP110074:c571345-571140 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTATTGCAAAACTAATCATCAGTCC

Structures

Antitoxin