Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2488506..2488738 Replicon chromosome
Accession NZ_CP110072
Organism Enterococcus faecalis strain BE7

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag OLL88_RS12090 Protein ID WP_002355568.1
Coordinates 2488622..2488738 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2488506..2488711 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL88_RS12070 2483993..2485081 - 1089 WP_002355572.1 diacylglycerol kinase -
OLL88_RS12075 2485100..2486530 - 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OLL88_RS12080 2486530..2487999 - 1470 WP_002358701.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OLL88_RS12085 2487999..2488304 - 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
- 2488506..2488711 + 206 - - Antitoxin
OLL88_RS12090 2488622..2488738 - 117 WP_002355568.1 putative holin-like toxin Toxin
OLL88_RS12095 2488886..2490916 - 2031 WP_002378031.1 NAD-dependent DNA ligase LigA -
OLL88_RS12100 2491042..2493300 - 2259 WP_264554365.1 DNA helicase PcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T263051 WP_002355568.1 NZ_CP110072:c2488738-2488622 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT263051 NZ_CP110072:2488506-2488711 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References