Detailed information of TA system TA263021

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 41376..41590
• Replicon: plasmid pBE11_1
• Accession: NZ_CP110070
• Organism: Enterococcus faecalis strain BE11

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: OLL93_RS14355
• Protein ID: WP_002360667.1
• Coordinates: 41376..41486 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	41526..41590 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL93_RS14310	36610..37134	+	525	WP_002360677.1	hypothetical protein	-
OLL93_RS14315	37297..37917	+	621	WP_025188285.1	recombinase family protein	-
OLL93_RS14320	37907..38221	+	315	WP_025188489.1	hypothetical protein	-
OLL93_RS14325	38215..38439	+	225	WP_002414746.1	ultraviolet resistance protein UvrA repressor UvrC	-
OLL93_RS14330	38500..38709	+	210	WP_002399367.1	hypothetical protein	-
OLL93_RS14335	38721..39023	+	303	WP_002393766.1	DUF6440 family protein	-
OLL93_RS14340	39451..40778	+	1328	Protein_48	Y-family DNA polymerase	-
OLL93_RS14345	40775..41125	+	351	WP_010784817.1	hypothetical protein	-
OLL93_RS14350	41082..41294	+	213	WP_002406179.1	hypothetical protein	-
OLL93_RS14355	41376..41486	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	41526..41590	-	65	-	-	Antitoxin
OLL93_RS14360	41726..42016	+	291	WP_001137528.1	hypothetical protein	-
OLL93_RS14365	42120..42491	-	372	WP_000049959.1	replication-associated protein RepC	-
OLL93_RS14370	42484..43329	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..43800	43800

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T263021 WP_002360667.1 NZ_CP110070:41376-41486 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT263021 NZ_CP110070:c41590-41526 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin