Detailed information of TA system TA263001

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2893461..2893753
• Replicon: chromosome
• Accession: NZ_CP110068
• Organism: Enterococcus faecalis strain BE13

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM02_RS14145
• Protein ID: WP_023894767.1
• Coordinates: 2893461..2893565 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2893498..2893753 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM02_RS14125	2888603..2888818	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
OLM02_RS14130	2888957..2889949	+	993	WP_010821958.1	biotin--[acetyl-CoA-carboxylase] ligase	-
OLM02_RS14135	2890213..2890851	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
OLM02_RS14140	2891536..2893152	+	1617	WP_010826271.1	phosphatase PAP2/LCP family protein	-
OLM02_RS14145	2893461..2893565	+	105	WP_023894767.1	putative holin-like toxin	Toxin
-	2893498..2893753	-	256	-	-	Antitoxin
OLM02_RS14150	2893755..2896607	-	2853	WP_229229141.1	WxL domain-containing protein	-
OLM02_RS14155	2897019..2897534	-	516	WP_010821961.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T263001 WP_023894767.1 NZ_CP110068:2893461-2893565 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 256 bp

>AT263001 NZ_CP110068:c2893753-2893498 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTTAAATAGGAGGTTTGGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTTAAA
AATAACCGTGCTTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGTGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin