Detailed information of TA system TA262997

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2813386..2813828
• Replicon: chromosome
• Accession: NZ_CP110068
• Organism: Enterococcus faecalis strain BE13

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM02_RS13785
• Protein ID: WP_023894767.1
• Coordinates: 2813386..2813490 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2813642..2813828 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM02_RS13770	2808682..2811426	+	2745	WP_025190234.1	glycosyl hydrolase family 65 protein	-
OLM02_RS13775	2811441..2812091	+	651	WP_010821928.1	beta-phosphoglucomutase	-
OLM02_RS13780	2812553..2813146	+	594	WP_010706987.1	PBECR4 domain-containing protein	-
OLM02_RS13785	2813386..2813490	-	105	WP_023894767.1	putative holin-like toxin	Toxin
-	2813642..2813828	+	187	-	-	Antitoxin
OLM02_RS13790	2813761..2813904	-	144	WP_010821929.1	type I toxin-antitoxin system toxin PepG1	-
OLM02_RS13795	2814137..2815108	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
OLM02_RS13800	2815283..2815720	-	438	WP_010821930.1	peptide-methionine (R)-S-oxide reductase MsrB	-
OLM02_RS13805	2815853..2816407	-	555	WP_002419630.1	Maf family protein	-
OLM02_RS13810	2816432..2818564	-	2133	WP_010821931.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T262997 WP_023894767.1 NZ_CP110068:c2813490-2813386 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT262997 NZ_CP110068:2813642-2813828 [Enterococcus faecalis]
TGTGCTATAATGAAAACAAAAAGAGAGATATGGGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin