Detailed information of TA system TA262964

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2664810..2665067
• Replicon: chromosome
• Accession: NZ_CP110063
• Organism: Enterococcus faecalis strain BE15

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL96_RS13095
• Protein ID: WP_021164441.1
• Coordinates: 2664966..2665067 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2664810..2665017 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL96_RS13070	2660494..2661447	-	954	WP_264526425.1	siderophore ABC transporter substrate-binding protein	-
OLL96_RS13075	2661486..2662241	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLL96_RS13080	2662238..2663203	-	966	WP_174092882.1	iron chelate uptake ABC transporter family permease subunit	-
OLL96_RS13085	2663200..2664147	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLL96_RS13090	2664332..2664784	+	453	WP_002389410.1	YueI family protein	-
-	2664810..2665017	+	208	-	-	Antitoxin
OLL96_RS13095	2664966..2665067	-	102	WP_021164441.1	putative holin-like toxin	Toxin
OLL96_RS13100	2665399..2665500	-	102	WP_075551663.1	putative holin-like toxin	-
OLL96_RS13105	2665690..2667960	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLL96_RS13110	2668131..2668631	+	501	WP_002372831.1	cysteine hydrolase family protein	-
OLL96_RS13115	2669030..2669926	+	897	WP_002389477.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T262964 WP_021164441.1 NZ_CP110063:c2665067-2664966 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 208 bp

>AT262964 NZ_CP110063:2664810-2665017 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATAAAGATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTAT
TTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin