Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2619064..2619324 Replicon chromosome
Accession NZ_CP110059
Organism Enterococcus faecalis strain BE16

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OLL92_RS12800 Protein ID WP_075551663.1
Coordinates 2619223..2619324 (-) Length 34 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2619064..2619274 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL92_RS12775 (2614748) 2614748..2615701 - 954 WP_002370087.1 siderophore ABC transporter substrate-binding protein -
OLL92_RS12780 (2615740) 2615740..2616495 - 756 WP_002354962.1 ATP-binding cassette domain-containing protein -
OLL92_RS12785 (2616492) 2616492..2617457 - 966 WP_002371665.1 iron chelate uptake ABC transporter family permease subunit -
OLL92_RS12790 (2617454) 2617454..2618401 - 948 WP_002354960.1 iron chelate uptake ABC transporter family permease subunit -
OLL92_RS12795 (2618586) 2618586..2619038 + 453 WP_002354958.1 YueI family protein -
- (2619064) 2619064..2619274 + 211 NuclAT_3 - Antitoxin
- (2619101) 2619101..2619278 + 178 NuclAT_9 - -
OLL92_RS12800 (2619223) 2619223..2619324 - 102 WP_075551663.1 putative holin-like toxin Toxin
OLL92_RS12805 (2619513) 2619513..2621783 - 2271 WP_002354955.1 bifunctional glutamate--cysteine ligase/glutathione synthetase -
OLL92_RS12810 (2621954) 2621954..2622454 + 501 WP_002361021.1 cysteine hydrolase family protein -
OLL92_RS12815 (2623009) 2623009..2623905 + 897 WP_104875316.1 YitT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-33)


Sequences

Toxin        


Download         Length: 34 a.a.        Molecular weight: 3599.34 Da        Isoelectric Point: 4.5869

>T262942 WP_075551663.1 NZ_CP110059:c2619324-2619223 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Download         Length: 102 bp

Antitoxin


Download         Length: 211 bp

>AT262942 NZ_CP110059:2619064-2619274 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCG
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References