Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 514080..514312 Replicon chromosome
Accession NZ_CP110054
Organism Enterococcus faecalis strain BE17

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OLL95_RS02590 Protein ID WP_033597376.1
Coordinates 514080..514196 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 514107..514312 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL95_RS02580 (509518) 509518..511776 + 2259 WP_104875437.1 DNA helicase PcrA -
OLL95_RS02585 (511902) 511902..513932 + 2031 WP_002358699.1 NAD-dependent DNA ligase LigA -
OLL95_RS02590 (514080) 514080..514196 + 117 WP_033597376.1 putative holin-like toxin Toxin
- (514107) 514107..514312 - 206 NuclAT_2 - Antitoxin
OLL95_RS02595 (514514) 514514..514819 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
OLL95_RS02600 (514819) 514819..516288 + 1470 WP_104875436.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OLL95_RS02605 (516288) 516288..517718 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OLL95_RS02610 (517737) 517737..518825 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4108.01 Da        Isoelectric Point: 5.9482

>T262916 WP_033597376.1 NZ_CP110054:514080-514196 [Enterococcus faecalis]
MFLSVEAALGLMISFAILVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT262916 NZ_CP110054:c514312-514107 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTATTGCAAAACTAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References