Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2664227..2664563 Replicon chromosome
Accession NZ_CP110053
Organism Enterococcus faecalis strain BE25

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag OLL87_RS12845 Protein ID WP_002396786.1
Coordinates 2664227..2664370 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2664514..2664563 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL87_RS12830 (2659944) 2659944..2660576 - 633 WP_002358972.1 RloB family protein -
OLL87_RS12835 (2660585) 2660585..2661880 - 1296 WP_010820355.1 ATP-binding protein -
OLL87_RS12840 (2662342) 2662342..2663958 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
OLL87_RS12845 (2664227) 2664227..2664370 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2664514) 2664514..2664563 + 50 NuclAT_8 - Antitoxin
- (2664302) 2664302..2664564 - 263 NuclAT_7 - -
OLL87_RS12850 (2664565) 2664565..2669256 - 4692 WP_083578718.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T262913 WP_002396786.1 NZ_CP110053:2664227-2664370 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT262913 NZ_CP110053:2664514-2664563 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References