Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 498182..498426 Replicon chromosome
Accession NZ_CP110053
Organism Enterococcus faecalis strain BE25

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OLL87_RS02475 Protein ID WP_225582204.1
Coordinates 498182..498310 (+) Length 43 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 498221..498426 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL87_RS02465 (493632) 493632..495890 + 2259 WP_083578645.1 DNA helicase PcrA -
OLL87_RS02470 (496016) 496016..498046 + 2031 WP_002407344.1 NAD-dependent DNA ligase LigA -
OLL87_RS02475 (498182) 498182..498310 + 129 WP_225582204.1 putative holin-like toxin Toxin
- (498221) 498221..498426 - 206 NuclAT_2 - Antitoxin
OLL87_RS02480 (498628) 498628..498933 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
OLL87_RS02485 (498933) 498933..500402 + 1470 WP_002398120.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OLL87_RS02490 (500402) 500402..501832 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OLL87_RS02495 (501851) 501851..502939 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(7-39)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4453.43 Da        Isoelectric Point: 8.9940

>T262898 WP_225582204.1 NZ_CP110053:498182-498310 [Enterococcus faecalis]
MKGAMFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 129 bp

Antitoxin


Download         Length: 206 bp

>AT262898 NZ_CP110053:c498426-498221 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References