Detailed information of TA system TA262891

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2815482..2815818
• Replicon: chromosome
• Accession: NZ_CP110050
• Organism: Enterococcus faecalis strain BE32

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: A0A125WAU0
• Locus tag: OLM04_RS13635
• Protein ID: WP_002391551.1
• Coordinates: 2815482..2815625 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2815769..2815818 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM04_RS13620	2811198..2811830	-	633	WP_002358972.1	RloB family protein	-
OLM04_RS13625	2811839..2813134	-	1296	WP_002371641.1	ATP-binding protein	-
OLM04_RS13630	2813596..2815212	+	1617	WP_002365430.1	phosphatase PAP2/LCP family protein	-
OLM04_RS13635	2815482..2815625	+	144	WP_002391551.1	putative holin-like toxin	Toxin
-	2815769..2815818	+	50	-	-	Antitoxin
OLM04_RS13640	2815820..2820511	-	4692	WP_002399468.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5175.17 Da
• Isoelectric Point: 8.6389

>T262891 WP_002391551.1 NZ_CP110050:2815482-2815625 [Enterococcus faecalis]
MNVSTKIYEKRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 50 bp

>AT262891 NZ_CP110050:2815769-2815818 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Structures

Toxin

• AlphaFold DB: A0A125WAU0

Antitoxin