Detailed information of TA system TA262885

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2647514..2647773
• Replicon: chromosome
• Accession: NZ_CP110050
• Organism: Enterococcus faecalis strain BE32

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM04_RS12850
• Protein ID: WP_075551663.1
• Coordinates: 2647672..2647773 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2647514..2647723 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM04_RS12820	2642764..2643717	-	954	WP_264522659.1	siderophore ABC transporter substrate-binding protein	-
OLM04_RS12825	2643756..2644511	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLM04_RS12830	2644508..2645473	-	966	WP_002365351.1	iron chelate uptake ABC transporter family permease subunit	-
OLM04_RS12835	2645470..2646417	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLM04_RS12840	2646602..2647054	+	453	WP_002354958.1	YueI family protein	-
OLM04_RS12845	2647239..2647340	-	102	WP_075551663.1	putative holin-like toxin	-
-	2647514..2647723	+	210	-	-	Antitoxin
OLM04_RS12850	2647672..2647773	-	102	WP_075551663.1	putative holin-like toxin	Toxin
OLM04_RS12855	2647962..2650232	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLM04_RS12860	2650403..2650903	+	501	WP_002365352.1	cysteine hydrolase family protein	-
OLM04_RS12865	2651302..2652198	+	897	WP_002365354.1	YitT family protein	-
OLM04_RS12870	2652249..2652647	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	tet(M)	-	2639822..2688747	48925

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T262885 WP_075551663.1 NZ_CP110050:c2647773-2647672 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT262885 NZ_CP110050:2647514-2647723 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin