Detailed information of TA system TA262869

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2815557..2815893
• Replicon: chromosome
• Accession: NZ_CP110047
• Organism: Enterococcus faecalis strain BE33

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: A0A125WAU0
• Locus tag: OLL90_RS13655
• Protein ID: WP_002391551.1
• Coordinates: 2815557..2815700 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2815844..2815893 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL90_RS13640	2811273..2811905	-	633	WP_002358972.1	RloB family protein	-
OLL90_RS13645	2811914..2813209	-	1296	WP_002371641.1	ATP-binding protein	-
OLL90_RS13650	2813671..2815287	+	1617	WP_002365430.1	phosphatase PAP2/LCP family protein	-
OLL90_RS13655	2815557..2815700	+	144	WP_002391551.1	putative holin-like toxin	Toxin
-	2815844..2815893	+	50	-	-	Antitoxin
OLL90_RS13660	2815895..2820586	-	4692	WP_002399468.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5175.17 Da
• Isoelectric Point: 8.6389

>T262869 WP_002391551.1 NZ_CP110047:2815557-2815700 [Enterococcus faecalis]
MNVSTKIYEKRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 50 bp

>AT262869 NZ_CP110047:2815844-2815893 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Structures

Toxin

• AlphaFold DB: A0A125WAU0

Antitoxin