Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2815557..2815894 Replicon chromosome
Accession NZ_CP110047
Organism Enterococcus faecalis strain BE33

Toxin (Protein)


Gene name txpA Uniprot ID A0A125WAU0
Locus tag OLL90_RS13655 Protein ID WP_002391551.1
Coordinates 2815557..2815700 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2815632..2815894 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL90_RS13640 2811273..2811905 - 633 WP_002358972.1 RloB family protein -
OLL90_RS13645 2811914..2813209 - 1296 WP_002371641.1 ATP-binding protein -
OLL90_RS13650 2813671..2815287 + 1617 WP_002365430.1 phosphatase PAP2/LCP family protein -
OLL90_RS13655 2815557..2815700 + 144 WP_002391551.1 putative holin-like toxin Toxin
- 2815632..2815894 - 263 - - Antitoxin
OLL90_RS13660 2815895..2820586 - 4692 WP_002399468.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5175.17 Da        Isoelectric Point: 8.6389

>T262867 WP_002391551.1 NZ_CP110047:2815557-2815700 [Enterococcus faecalis]
MNVSTKIYEKRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT262867 NZ_CP110047:c2815894-2815632 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A125WAU0

Antitoxin

Download structure file

References