Detailed information of TA system TA262848

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 27945..28150
• Replicon: plasmid pBE43_2
• Accession: NZ_CP110043
• Organism: Enterococcus faecalis strain BE43

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: OLM01_RS14650
• Protein ID: WP_002387930.1
• Coordinates: 27945..28046 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	28086..28150 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM01_RS14605	23186..23473	+	288	WP_010778046.1	hypothetical protein	-
OLM01_RS14615	24776..25000	+	225	WP_002395938.1	ultraviolet resistance protein UvrA repressor UvrC	-
OLM01_RS14620	25061..25270	+	210	WP_064686952.1	hypothetical protein	-
OLM01_RS14625	25282..25455	+	174	WP_002395320.1	hypothetical protein	-
OLM01_RS14630	25473..25583	+	111	WP_229235047.1	DUF6440 family protein	-
OLM01_RS14635	26010..27338	+	1329	WP_010717412.1	ultraviolet resistance protein UvrA	-
OLM01_RS14640	27335..27685	+	351	WP_002395322.1	hypothetical protein	-
OLM01_RS14645	27642..27854	+	213	WP_002395323.1	hypothetical protein	-
OLM01_RS14650	27945..28046	+	102	WP_002387930.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	28086..28150	-	65	-	-	Antitoxin
OLM01_RS14655	28287..28583	+	297	WP_010717413.1	hypothetical protein	-
OLM01_RS14660	28837..29619	+	783	WP_002369746.1	ParA family protein	-
OLM01_RS14665	29612..29968	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..30227	30227

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3731.42 Da
• Isoelectric Point: 4.1672

>T262848 WP_002387930.1 NZ_CP110043:27945-28046 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT262848 NZ_CP110043:c28150-28086 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin