Detailed information of TA system TA262838

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2815642..2815908
• Replicon: chromosome
• Accession: NZ_CP110041
• Organism: Enterococcus faecalis strain BE43

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM01_RS13810
• Protein ID: WP_002411240.1
• Coordinates: 2815642..2815791 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2815724..2815908 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM01_RS13790	2810763..2810978	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
OLM01_RS13795	2811117..2812109	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
OLM01_RS13800	2812373..2813011	-	639	WP_073438309.1	lytic polysaccharide monooxygenase	-
OLM01_RS13805	2813697..2815313	+	1617	WP_002406969.1	phosphatase PAP2/LCP family protein	-
OLM01_RS13810	2815642..2815791	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2815724..2815908	-	185	-	-	Antitoxin
OLM01_RS13815	2815910..2816050	+	141	WP_073340360.1	putative holin-like toxin	-
OLM01_RS13820	2816281..2816424	+	144	WP_073437820.1	putative holin-like toxin	-
OLM01_RS13825	2816557..2817516	+	960	WP_002360751.1	IS30-like element IS1062 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2816557..2817516	959

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T262838 WP_002411240.1 NZ_CP110041:2815642-2815791 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT262838 NZ_CP110041:c2815908-2815724 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin