Detailed information of TA system TA262832

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2664950..2665434
• Replicon: chromosome
• Accession: NZ_CP110041
• Organism: Enterococcus faecalis strain BE43

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM01_RS13115
• Protein ID: WP_021164441.1
• Coordinates: 2664950..2665051 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2665225..2665434 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM01_RS13090	2660478..2661431	-	954	WP_264526425.1	siderophore ABC transporter substrate-binding protein	-
OLM01_RS13095	2661470..2662225	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLM01_RS13100	2662222..2663187	-	966	WP_174092882.1	iron chelate uptake ABC transporter family permease subunit	-
OLM01_RS13105	2663184..2664131	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLM01_RS13110	2664316..2664768	+	453	WP_002389410.1	YueI family protein	-
OLM01_RS13115	2664950..2665051	-	102	WP_021164441.1	putative holin-like toxin	Toxin
-	2665225..2665434	+	210	-	-	Antitoxin
OLM01_RS13120	2665383..2665484	-	102	WP_075551663.1	putative holin-like toxin	-
OLM01_RS13125	2665674..2667944	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLM01_RS13130	2668115..2668615	+	501	WP_002372831.1	cysteine hydrolase family protein	-
OLM01_RS13135	2669014..2669910	+	897	WP_002389477.1	YitT family protein	-
OLM01_RS13140	2669961..2670359	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T262832 WP_021164441.1 NZ_CP110041:c2665051-2664950 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT262832 NZ_CP110041:2665225-2665434 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin