Detailed information of TA system TA262822

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2651029..2651330
• Replicon: chromosome
• Accession: NZ_CP110040
• Organism: Enterococcus faecalis strain BE45

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM07_RS12990
• Protein ID: WP_002415596.1
• Coordinates: 2651029..2651172 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2651105..2651330 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM07_RS12975 (2646684)	2646684..2647316	-	633	WP_002358972.1	RloB family protein	-
OLM07_RS12980 (2647325)	2647325..2648620	-	1296	WP_264547459.1	AAA family ATPase	-
OLM07_RS12985 (2649082)	2649082..2650698	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
OLM07_RS12990 (2651029)	2651029..2651172	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2651105)	2651105..2651330	-	226	NuclAT_4	-	Antitoxin
- (2651146)	2651146..2651330	-	185	NuclAT_6	-	-
- (2651312)	2651312..2651362	+	51	NuclAT_8	-	-
OLM07_RS12995 (2651363)	2651363..2654833	-	3471	WP_264547460.1	WxL domain-containing protein	-
OLM07_RS13000 (2654890)	2654890..2656041	-	1152	WP_016632326.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T262822 WP_002415596.1 NZ_CP110040:2651029-2651172 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 226 bp

>AT262822 NZ_CP110040:c2651330-2651105 [Enterococcus faecalis]
AGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATAATGGTAATGAAAAGAGAGATATGCTGTAACAT
ACCTCTCTAGTGTAGAGCCGTTTCAGACGGTGACCTTTTTAGTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTT
ATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin