Detailed information of TA system TA262811

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2662818..2663119
• Replicon: chromosome
• Accession: NZ_CP110039
• Organism: Enterococcus faecalis strain BE47

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM03_RS13030
• Protein ID: WP_002415596.1
• Coordinates: 2662818..2662961 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2662894..2663119 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM03_RS13015 (2658473)	2658473..2659105	-	633	WP_002358972.1	RloB family protein	-
OLM03_RS13020 (2659114)	2659114..2660409	-	1296	WP_264547459.1	AAA family ATPase	-
OLM03_RS13025 (2660871)	2660871..2662487	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
OLM03_RS13030 (2662818)	2662818..2662961	+	144	WP_002415596.1	type I toxin-antitoxin system toxin PepG1	Toxin
- (2662894)	2662894..2663119	-	226	NuclAT_4	-	Antitoxin
- (2662935)	2662935..2663119	-	185	NuclAT_6	-	-
- (2663101)	2663101..2663151	+	51	NuclAT_8	-	-
OLM03_RS13035 (2663152)	2663152..2666622	-	3471	WP_264547460.1	WxL domain-containing protein	-
OLM03_RS13040 (2666679)	2666679..2667830	-	1152	WP_016632326.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5314.46 Da
• Isoelectric Point: 10.6323

>T262811 WP_002415596.1 NZ_CP110039:2662818-2662961 [Enterococcus faecalis]
MNVSAKIYERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 226 bp

>AT262811 NZ_CP110039:c2663119-2662894 [Enterococcus faecalis]
AGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATAATGGTAATGAAAAGAGAGATATGCTGTAACAT
ACCTCTCTAGTGTAGAGCCGTTTCAGACGGTGACCTTTTTAGTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTT
ATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin