Detailed information of TA system TA262807

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2588041..2588301
• Replicon: chromosome
• Accession: NZ_CP110039
• Organism: Enterococcus faecalis strain BE47

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLM03_RS12695
• Protein ID: WP_016630771.1
• Coordinates: 2588158..2588301 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2588041..2588225 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLM03_RS12680 (2583602)	2583602..2584315	-	714	WP_002354877.1	trehalose operon repressor	-
OLM03_RS12685 (2584577)	2584577..2587321	+	2745	WP_016630773.1	glycosyl hydrolase family 65 protein	-
OLM03_RS12690 (2587336)	2587336..2587986	+	651	WP_016630772.1	beta-phosphoglucomutase	-
- (2588055)	2588055..2588184	+	130	NuclAT_7	-	-
- (2588041)	2588041..2588225	+	185	NuclAT_5	-	Antitoxin
OLM03_RS12695 (2588158)	2588158..2588301	-	144	WP_016630771.1	type I toxin-antitoxin system toxin PepG1	Toxin
OLM03_RS12700 (2588533)	2588533..2589504	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
OLM03_RS12705 (2589679)	2589679..2590116	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
OLM03_RS12710 (2590249)	2590249..2590803	-	555	WP_002354869.1	Maf family protein	-
OLM03_RS12715 (2590828)	2590828..2592870	-	2043	WP_264547450.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5310.47 Da
• Isoelectric Point: 10.8331

>T262807 WP_016630771.1 NZ_CP110039:c2588301-2588158 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYEKIQTILGFGMFTVALIALIVKLLKNDNKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT262807 NZ_CP110039:2588041-2588225 [Enterococcus faecalis]
TGCTAGAATGTAGATGAAAAGAGAGAGATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCAATTGT
ATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGTGCA
ATCAAAGCAACGGTAAACATACCAA

Structures

Antitoxin