Detailed information of TA system TA262801

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 203422..203679
• Replicon: chromosome
• Accession: NZ_CP110036
• Organism: Enterococcus faecalis strain BE52

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL99_RS00925
• Protein ID: WP_021164441.1
• Coordinates: 203422..203523 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	203472..203679 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL99_RS00905	198563..199459	-	897	WP_002389477.1	YitT family protein	-
OLL99_RS00910	199858..200358	-	501	WP_002372831.1	cysteine hydrolase family protein	-
OLL99_RS00915	200529..202799	+	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLL99_RS00920	202989..203090	+	102	WP_075551663.1	putative holin-like toxin	-
OLL99_RS00925	203422..203523	+	102	WP_021164441.1	putative holin-like toxin	Toxin
-	203472..203679	-	208	-	-	Antitoxin
OLL99_RS00930	203705..204157	-	453	WP_002389410.1	YueI family protein	-
OLL99_RS00935	204343..205290	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLL99_RS00940	205287..206252	+	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
OLL99_RS00945	206249..207004	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLL99_RS00950	207043..207996	+	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T262801 WP_021164441.1 NZ_CP110036:203422-203523 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 208 bp

>AT262801 NZ_CP110036:c203679-203472 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATAAAGATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTAT
TTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin