Detailed information of TA system TA262796

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 202989..203248
• Replicon: chromosome
• Accession: NZ_CP110036
• Organism: Enterococcus faecalis strain BE52

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL99_RS00920
• Protein ID: WP_075551663.1
• Coordinates: 202989..203090 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	203039..203248 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL99_RS00900	198114..198512	+	399	WP_002354951.1	glyoxalase	-
OLL99_RS00905	198563..199459	-	897	WP_002389477.1	YitT family protein	-
OLL99_RS00910	199858..200358	-	501	WP_002372831.1	cysteine hydrolase family protein	-
OLL99_RS00915	200529..202799	+	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OLL99_RS00920	202989..203090	+	102	WP_075551663.1	putative holin-like toxin	Toxin
-	203039..203248	-	210	-	-	Antitoxin
OLL99_RS00925	203422..203523	+	102	WP_021164441.1	putative holin-like toxin	-
OLL99_RS00930	203705..204157	-	453	WP_002389410.1	YueI family protein	-
OLL99_RS00935	204343..205290	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
OLL99_RS00940	205287..206252	+	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
OLL99_RS00945	206249..207004	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OLL99_RS00950	207043..207996	+	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T262796 WP_075551663.1 NZ_CP110036:202989-203090 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT262796 NZ_CP110036:c203248-203039 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin