Detailed information of TA system TA262793

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 131883..132145
• Replicon: chromosome
• Accession: NZ_CP110036
• Organism: Enterococcus faecalis strain BE52

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL99_RS00590
• Protein ID: WP_002367458.1
• Coordinates: 131883..132026 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	131959..132145 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL99_RS00570	127224..129356	+	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-
OLL99_RS00575	129381..129935	+	555	WP_002389433.1	nucleoside triphosphate pyrophosphatase	-
OLL99_RS00580	130068..130505	+	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
OLL99_RS00585	130680..131651	+	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
OLL99_RS00590	131883..132026	+	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	131959..132145	-	187	-	-	Antitoxin
OLL99_RS00595	132266..132859	-	594	WP_002389391.1	PBECR4 domain-containing protein	-
OLL99_RS00600	133279..133929	-	651	WP_002389419.1	beta-phosphoglucomutase	-
OLL99_RS00605	133944..136688	-	2745	WP_002411259.1	glycosyl hydrolase family 65 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T262793 WP_002367458.1 NZ_CP110036:131883-132026 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT262793 NZ_CP110036:c132145-131959 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin