262790

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 52186..52452 Replicon chromosome
Accession NZ_CP110036
Organism Enterococcus faecalis strain BE52

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OLL99_RS00240 Protein ID WP_002411240.1
Coordinates 52303..52452 (-) Length 50 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 52186..52370 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL99_RS00230 51669..51812 - 144 WP_073437820.1 putative holin-like toxin -
OLL99_RS00235 52011..52184 - 174 WP_264526575.1 putative holin-like toxin -
- 52186..52370 + 185 - - Antitoxin
OLL99_RS00240 52303..52452 - 150 WP_002411240.1 type I toxin-antitoxin system toxin PepG1 Toxin
OLL99_RS00245 52781..54397 - 1617 WP_002406969.1 phosphatase PAP2/LCP family protein -
OLL99_RS00250 55083..55721 + 639 WP_073438309.1 lytic polysaccharide monooxygenase -
OLL99_RS00255 55985..56977 - 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
OLL99_RS00260 57116..57331 + 216 WP_002354768.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(16-49)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5738.05 Da        Isoelectric Point: 11.3858

>T262790 WP_002411240.1 NZ_CP110036:c52452-52303 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 150 bp

Antitoxin


Download         Length: 185 bp

>AT262790 NZ_CP110036:52186-52370 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References