Detailed information of TA system TA262788

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 52011..52370
• Replicon: chromosome
• Accession: NZ_CP110036
• Organism: Enterococcus faecalis strain BE52

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL99_RS00235
• Protein ID: WP_264526575.1
• Coordinates: 52011..52184 (-)
• Length: 58 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	52186..52370 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL99_RS00230	51669..51812	-	144	WP_073437820.1	putative holin-like toxin	-
OLL99_RS00235	52011..52184	-	174	WP_264526575.1	putative holin-like toxin	Toxin
-	52186..52370	+	185	-	-	Antitoxin
OLL99_RS00240	52303..52452	-	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	-
OLL99_RS00245	52781..54397	-	1617	WP_002406969.1	phosphatase PAP2/LCP family protein	-
OLL99_RS00250	55083..55721	+	639	WP_073438309.1	lytic polysaccharide monooxygenase	-
OLL99_RS00255	55985..56977	-	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
OLL99_RS00260	57116..57331	+	216	WP_002354768.1	zinc ribbon domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-46)

Sequences

Toxin

Protein

• Length: 58 a.a.
• Molecular weight: 6615.88 Da
• Isoelectric Point: 9.7346

>T262788 WP_264526575.1 NZ_CP110036:c52184-52011 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKKITVYFDQYGYF

Nucleotide

• Length: 174 bp

Antitoxin

Nucleotide

• Length: 185 bp

>AT262788 NZ_CP110036:52186-52370 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin