Detailed information of TA system TA262781

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 51475..51812
• Replicon: chromosome
• Accession: NZ_CP110036
• Organism: Enterococcus faecalis strain BE52

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OLL99_RS00230
• Protein ID: WP_073437820.1
• Coordinates: 51669..51812 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	51475..51737 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLL99_RS00225	46783..51474	+	4692	WP_085345106.1	WxL domain-containing protein	-
-	51475..51737	+	263	-	-	Antitoxin
OLL99_RS00230	51669..51812	-	144	WP_073437820.1	putative holin-like toxin	Toxin
OLL99_RS00235	52011..52184	-	174	WP_264526575.1	putative holin-like toxin	-
OLL99_RS00240	52303..52452	-	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	-
OLL99_RS00245	52781..54397	-	1617	WP_002406969.1	phosphatase PAP2/LCP family protein	-
OLL99_RS00250	55083..55721	+	639	WP_073438309.1	lytic polysaccharide monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5274.27 Da
• Isoelectric Point: 8.6626

>T262781 WP_073437820.1 NZ_CP110036:c51812-51669 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFEILEAVKENNKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 263 bp

>AT262781 NZ_CP110036:51475-51737 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGGCGTTGTGCTACA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATATCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTTTTCTTTTACAGCCTCTAGGATTTCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Structures

Antitoxin