Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2786630..2786824 Replicon chromosome
Accession NZ_CP110020
Organism Enterococcus faecalis strain BE69

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag OLM05_RS13400 Protein ID WP_015543884.1
Coordinates 2786630..2786725 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2786760..2786824 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLM05_RS13380 (2781806) 2781806..2782921 + 1116 WP_002383680.1 FAD-dependent oxidoreductase -
OLM05_RS13385 (2782990) 2782990..2784144 - 1155 WP_002383679.1 mannitol-1-phosphate 5-dehydrogenase -
OLM05_RS13390 (2784159) 2784159..2784596 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
OLM05_RS13395 (2784611) 2784611..2786383 - 1773 WP_010715007.1 PTS mannitol-specific transporter subunit IIBC -
OLM05_RS13400 (2786630) 2786630..2786725 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- (2786760) 2786760..2786824 - 65 NuclAT_13 - Antitoxin
OLM05_RS13405 (2786995) 2786995..2787429 - 435 WP_002355276.1 PTS sugar transporter subunit IIA -
OLM05_RS13410 (2787440) 2787440..2789473 - 2034 WP_002383677.1 BglG family transcription antiterminator -
OLM05_RS13415 (2789464) 2789464..2791212 - 1749 WP_002383675.1 PTS transporter subunit EIIC -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T262780 WP_015543884.1 NZ_CP110020:2786630-2786725 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T262780 NZ_CP110020:2786630-2786725 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 65 bp

>AT262780 NZ_CP110020:c2786824-2786760 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References