262766

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 384524..384778 Replicon chromosome
Accession NZ_CP110019
Organism Enterococcus faecalis strain BE70

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag OLM00_RS01915 Protein ID WP_002355568.1
Coordinates 384524..384640 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 384623..384778 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLM00_RS01905 (379962) 379962..382220 + 2259 WP_002363179.1 DNA helicase PcrA -
OLM00_RS01910 (382346) 382346..384376 + 2031 WP_002375948.1 NAD-dependent DNA ligase LigA -
OLM00_RS01915 (384524) 384524..384640 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (384551) 384551..384756 - 206 NuclAT_4 - -
- (384623) 384623..384758 - 136 NuclAT_10 - -
- (384623) 384623..384778 - 156 NuclAT_8 - Antitoxin
OLM00_RS01920 (384958) 384958..385263 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
OLM00_RS01925 (385263) 385263..386742 + 1480 Protein_353 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OLM00_RS01930 (386732) 386732..388161 + 1430 Protein_354 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OLM00_RS01935 (388180) 388180..389267 + 1088 Protein_355 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T262766 WP_002355568.1 NZ_CP110019:384524-384640 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 156 bp

>AT262766 NZ_CP110019:c384778-384623 [Enterococcus faecalis]
GAACTATGTTATTATGAAAATGAAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACCAGTTATAAGAACTG
GTGGCTTACTGAGTTATTGGTTTTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References