Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1183882..1184404 Replicon chromosome
Accession NZ_CP109947
Organism Pectobacterium cacticida strain CFCC10813

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OI450_RS05560 Protein ID WP_264498146.1
Coordinates 1183882..1184151 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OI450_RS05565 Protein ID WP_264498147.1
Coordinates 1184153..1184404 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI450_RS05545 (OI450_05545) 1180869..1182440 - 1572 WP_264498143.1 shufflon system plasmid conjugative transfer pilus tip adhesin PilV -
OI450_RS05550 (OI450_05550) 1182546..1183112 - 567 WP_264498144.1 type 4 pilus major pilin -
OI450_RS05555 (OI450_05555) 1183390..1183794 + 405 WP_264498145.1 H-NS family nucleoid-associated regulatory protein -
OI450_RS05560 (OI450_05560) 1183882..1184151 - 270 WP_264498146.1 Txe/YoeB family addiction module toxin Toxin
OI450_RS05565 (OI450_05565) 1184153..1184404 - 252 WP_264498147.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OI450_RS05570 (OI450_05570) 1184603..1184857 + 255 Protein_1067 YegP family protein -
OI450_RS05575 (OI450_05575) 1184937..1185485 + 549 WP_264498148.1 hypothetical protein -
OI450_RS05580 (OI450_05580) 1185626..1186834 + 1209 WP_264495962.1 IS256 family transposase -
OI450_RS05585 (OI450_05585) 1186883..1187278 - 396 WP_264498149.1 hypothetical protein -
OI450_RS05590 (OI450_05590) 1187324..1187569 - 246 WP_264498150.1 DNA-binding protein -
OI450_RS05595 (OI450_05595) 1187638..1187940 - 303 WP_039325217.1 hypothetical protein -
OI450_RS05600 (OI450_05600) 1188013..1188297 - 285 WP_264498151.1 hypothetical protein -
OI450_RS05605 (OI450_05605) 1188447..1188647 - 201 WP_264498152.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1175436..1188647 13211
- flank IS/Tn - - 1185626..1186834 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10520.01 Da        Isoelectric Point: 9.7709

>T262488 WP_264498146.1 NZ_CP109947:c1184151-1183882 [Pectobacterium cacticida]
MKLLWTENAWQDYLYWQENDPGMVTKINDLIKDTKRSPFKGLGKPEPLKGDISGFWSRRISGEHRFVYRVSGKGEAQQLD
VVQCRFHYK

Download         Length: 270 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9303.60 Da        Isoelectric Point: 5.0873

>AT262488 WP_264498147.1 NZ_CP109947:c1184404-1184153 [Pectobacterium cacticida]
MAHVRLTEFRQNIAAHFDEVISSRAPLLVTRQGSEAMVMLAEGEYESILETLHLLSTPANTDRLRESIKQLGDGKVVERD
PTL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References