Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 1176027..1176721 Replicon chromosome
Accession NZ_CP109947
Organism Pectobacterium cacticida strain CFCC10813

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag OI450_RS05515 Protein ID WP_209428711.1
Coordinates 1176027..1176425 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag OI450_RS05520 Protein ID WP_027711146.1
Coordinates 1176428..1176721 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI450_RS05475 (OI450_05475) 1171442..1172056 + 615 WP_264498134.1 YrbL family protein -
OI450_RS05480 (OI450_05480) 1172295..1173173 + 879 WP_264498135.1 NAD(P)-dependent oxidoreductase -
OI450_RS05485 (OI450_05485) 1173489..1173980 + 492 WP_264498136.1 YhfG family protein -
OI450_RS05490 (OI450_05490) 1173973..1174557 + 585 WP_264498137.1 putative adenosine monophosphate-protein transferase Fic -
OI450_RS05495 (OI450_05495) 1174680..1174826 + 147 WP_264498138.1 hypothetical protein -
OI450_RS05500 (OI450_05500) 1174930..1175187 - 258 WP_039351569.1 BrnA antitoxin family protein -
OI450_RS05505 (OI450_05505) 1175260..1175487 - 228 Protein_1054 hypothetical protein -
OI450_RS05510 (OI450_05510) 1175487..1175903 - 417 Protein_1055 site-specific integrase -
OI450_RS05515 (OI450_05515) 1176027..1176425 - 399 WP_209428711.1 type II toxin-antitoxin system YafO family toxin Toxin
OI450_RS05520 (OI450_05520) 1176428..1176721 - 294 WP_027711146.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
OI450_RS05525 (OI450_05525) 1176982..1177722 + 741 WP_264498139.1 hypothetical protein -
OI450_RS05530 (OI450_05530) 1178067..1178231 + 165 WP_264498140.1 hypothetical protein -
OI450_RS05535 (OI450_05535) 1178281..1178745 - 465 WP_264498141.1 DUF6392 family protein -
OI450_RS05540 (OI450_05540) 1178745..1180553 - 1809 WP_264498142.1 S-type pyocin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1175436..1188647 13211


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15268.59 Da        Isoelectric Point: 7.5154

>T262487 WP_209428711.1 NZ_CP109947:c1176425-1176027 [Pectobacterium cacticida]
IRIFKSALIRKQLSQQELDDLAADFLSYKKDGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADADAPFPKFLRQFKRT
SDQAHLVYCQGAMDPDAYLLIIILKPEAHKMARNNNHMHKIGMMAEAFRMKH

Download         Length: 399 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10979.44 Da        Isoelectric Point: 4.9167

>AT262487 WP_027711146.1 NZ_CP109947:c1176721-1176428 [Pectobacterium cacticida]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVHTAARFRPSAERLSDIADSG
QKLLQNASDKDLTEFTE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References