Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2034411..2034930 Replicon chromosome
Accession NZ_CP109939
Organism Streptococcus suis strain ID36054

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0K2E7Z7
Locus tag OHM47_RS10120 Protein ID WP_013730620.1
Coordinates 2034411..2034668 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0K2E7Z9
Locus tag OHM47_RS10125 Protein ID WP_002939010.1
Coordinates 2034670..2034930 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHM47_RS10105 (OHM47_10105) 2030882..2032612 - 1731 WP_249547134.1 hypothetical protein -
OHM47_RS10110 (OHM47_10110) 2032975..2033847 - 873 WP_009910907.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
OHM47_RS10115 (OHM47_10115) 2033867..2034397 - 531 WP_009910909.1 DUF1697 domain-containing protein -
OHM47_RS10120 (OHM47_10120) 2034411..2034668 - 258 WP_013730620.1 Txe/YoeB family addiction module toxin Toxin
OHM47_RS10125 (OHM47_10125) 2034670..2034930 - 261 WP_002939010.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OHM47_RS10130 (OHM47_10130) 2035006..2035461 - 456 WP_013730621.1 8-oxo-dGTP diphosphatase -
OHM47_RS10135 (OHM47_10135) 2035465..2035833 - 369 WP_013730622.1 hypothetical protein -
OHM47_RS10140 (OHM47_10140) 2035826..2036395 - 570 WP_022540720.1 ribonuclease M5 -
OHM47_RS10145 (OHM47_10145) 2036379..2037161 - 783 WP_002939015.1 TatD family hydrolase -
OHM47_RS10150 (OHM47_10150) 2037269..2037406 - 138 WP_002939016.1 50S ribosomal protein L34 -
OHM47_RS10155 (OHM47_10155) 2037574..2038569 - 996 WP_012775367.1 RNA-binding cell elongation regulator Jag/EloR -
OHM47_RS10160 (OHM47_10160) 2038589..2039401 - 813 WP_012027897.1 YidC/Oxa1 family membrane protein insertase -
OHM47_RS10165 (OHM47_10165) 2039385..2039744 - 360 WP_004194560.1 ribonuclease P protein component -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10346.86 Da        Isoelectric Point: 8.0279

>T262460 WP_013730620.1 NZ_CP109939:c2034668-2034411 [Streptococcus suis]
MGIHFTDDAWEDYLYWQGQDKKTLKRINKIIKDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEADRLCILSL
KDHYR

Download         Length: 258 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9980.36 Da        Isoelectric Point: 5.7134

>AT262460 WP_002939010.1 NZ_CP109939:c2034930-2034670 [Streptococcus suis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAKVKTGQTQER
NLIEAD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2E7Z7

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2E7Z9

References