Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2724685..2724947 Replicon chromosome
Accession NZ_CP109933
Organism Staphylococcus aureus strain SASWT1215

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NT398_RS13605 Protein ID WP_001802298.1
Coordinates 2724685..2724789 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2724784..2724947 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NT398_RS13590 2721482..2722264 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
NT398_RS13595 2722332..2723189 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NT398_RS13600 2723847..2724005 - 159 WP_001792784.1 hypothetical protein -
NT398_RS13605 2724685..2724789 + 105 WP_001802298.1 hypothetical protein Toxin
- 2724784..2724947 - 164 - - Antitoxin
NT398_RS13615 2725222..2726313 - 1092 WP_000495669.1 hypothetical protein -
NT398_RS13620 2726579..2727556 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
NT398_RS13625 2727558..2727878 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NT398_RS13630 2728030..2728695 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T262446 WP_001802298.1 NZ_CP109933:2724685-2724789 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT262446 NZ_CP109933:c2724947-2724784 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References