262444

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2441496..2441680 Replicon chromosome
Accession NZ_CP109933
Organism Staphylococcus aureus strain SASWT1215

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag NT398_RS12125 Protein ID WP_000482652.1
Coordinates 2441496..2441603 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2441620..2441680 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NT398_RS12100 2436858..2437331 + 474 WP_000456486.1 GyrI-like domain-containing protein -
NT398_RS12105 2437454..2438665 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
NT398_RS12110 2438847..2439506 - 660 WP_000831298.1 membrane protein -
NT398_RS12115 2439566..2440708 - 1143 WP_001176863.1 glycerate kinase -
NT398_RS12120 2440976..2441362 + 387 WP_000779360.1 flippase GtxA -
NT398_RS12125 2441496..2441603 + 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2441620..2441680 - 61 - - Antitoxin
NT398_RS12130 2442306..2444069 + 1764 WP_001064825.1 ABC transporter ATP-binding protein -
NT398_RS12135 2444094..2445827 + 1734 WP_063653200.1 ABC transporter ATP-binding protein -
NT398_RS12140 2446094..2446225 + 132 WP_223197975.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T262444 WP_000482652.1 NZ_CP109933:2441496-2441603 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT262444 NZ_CP109933:c2441680-2441620 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References